A structure-based virtual high-throughput screening, molecular docking, molecular dynamics and MM/PBSA study identified novel putative drug-like dual inhibitors of trypanosomal cruzain and rhodesain cysteine proteases
Discovery of potent antiproliferative agents from selected oxygen heterocycles as EGFR tyrosine kinase inhibitors from the U.S. National Cancer Institute database by in silico screening and bioactivity evaluation
OXIDATIVE FRAGMENTATION OF CYTISINE AS AN ENTRY TO THE BIS(PIPERIDINE) SCAFFOLD OF VIRGIDIVARINE
Visible-light-mediated decarboxylative alkylation of 2-pyridone derivatives: Via a C3-selective C-H functionalization
In Silico-Guided Rational Drug Design and Semi-synthesis of C(2)-Functionalized Huperzine A Derivatives as Acetylcholinesterase Inhibitors
Identification of new 3-phenyl-1H-indole-2-carbohydrazide derivatives and their structure–activity relationships as potent tubulin inhibitors and anticancer agents: A combined in silico, in vitro and synthetic study
Iridium-Catalysed C-H Borylation of 2-Pyridones; Bisfunctionalisation of CC4
(-)-Cytisine: Access to a stereochemically defined and functionally flexible piperidine scaffold
Synthesis of Functionalized Alkenes by a Transition-Metal-Free Zweifel Coupling